Phage vB_AbaM_MU1 for biocontrol of carbapenem-resistant Acinetobacter baumannii (CRAB) isolated from wound infection.

ABSTRACT:

Background

Carbapenem-resistant Acinetobacter baumannii (CRAB) continues to pose significant public health in clinical settings due to its remarkable genomic plasticity and resistance to available therapeutic drugs, including carbapenems. Bacteriophage has emerged as an optimistic solution capable of addressing such drug resistance dilemma. This study represents a comprehensive characterization of a novel Acinetobacter phage with potential application against CRAB-associated wound infections.

Methods

Sewage sample was obtained, processed, and enriched with A. baumannii M13 phage(s) for the purpose of phages' isolation. The isolated phage was examined using transmission electron microscope (TEM) and identified in terms of host range and efficiency of plating through spot test

SUBMITTER: Sabry H 

PROVIDER: S-EPMC12930573 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature