TransFusion: a novel comprehensive platform for integration analysis of single-cell and spatial transcriptomics.

ABSTRACT:

Motivation

Understanding spatial organization, intercellular interactions, and regulatory networks within the spatial context of tissues is crucial for uncovering complex biological processes and disease mechanisms. Spatial transcriptomics technologies have revolutionized this field by enabling the spatially resolved profiling of gene expression. 10× Visium has emerged as the predominant spatial technology, but its low resolution and the complexity of integrating multimodal datasets present significant analytical challenges, particularly for researchers with limited computational and statistical expertise. Current spatial transcriptomics analysis platforms generally fall short of effectively integrating multimodal data and maximizing the utility of spatial information-such as uncov

SUBMITTER: Lin W 

PROVIDER: S-EPMC12930851 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature