Perirenal Fat Thickness Is Associated With Disturbed Circadian Blood Pressure Rhythm in Essential Hypertension.

ABSTRACT: Circadian blood pressure (BP) rhythm disturbances predict cardiovascular risk. Perirenal fat thickness (PRFT) may influence blood pressure regulation, but its role in key circadian phenotypes remains unclear. We examined whether PRFT is associated with disturbances in circadian BP rhythm and short-term blood pressure variability (BPV) in patients with essential hypertension, independently of traditional adiposity indices. In this cross-sectional study of 253 patients, PRFT and other adiposity indices were measured by abdominal CT. Circadian BP rhythm and variability were assessed via 24-hour ambulatory blood pressure monitoring (ABPM). Patients were stratified into PRFT tertiles for analysis. The high PRFT group (Tertile 3) exhibited a significantly higher prevalence of morning hypertensio

SUBMITTER: Wu S 

PROVIDER: S-EPMC12931219 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature