Association between angiotensin receptor-neprilysin inhibitor use and clinical outcomes in patients with heart failure: a 1-year prospective cohort study from Jordan.

ABSTRACT:

Objectives

Heart failure (HF) is associated with complex symptoms and frequent hospitalisation that reduce patients' quality of life (QoL). This study aims to assess the association between angiotensin receptor-neprilysin inhibitor (ARNI) use and changes in QoL and disease-related outcomes among patients with HF in Jordan.

Design

Prospective observational cohort study.

Setting and participants

The study was conducted among patients with HF attending the outpatient cardiology clinics at Jordan University Hospital, a tertiary care centre in Amman, Jordan. Patients either initiated on ARNI or receiving angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB) were included in the study at a 1:2 ratio. All participants were followed up for up to 1

SUBMITTER: Odeh RS 

PROVIDER: S-EPMC12931546 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature