Dynamic trends and determinants of COVID-19 vaccine hesitancy among adults in China during 2021-2022: A multilevel analysis based on four national cross-sectional surveys.

ABSTRACT: This study aimed to explore the dynamic trends and determinants of COVID-19 vaccine hesitancy among adults in China from 2021 to 2022, providing evidence for targeted vaccination strategies under different epidemic control phases. We conducted four large-scale, anonymous, cross-sectional online surveys in January 2021, June 2021, January 2022, and June 2022. Adults aged 18 and older were recruited nationwide, with demographic weighting based on the 2020 National Census. Vaccine hesitancy was defined according to WHO SAGE guidelines. Multilevel regression and post-stratification (MRP) were applied to estimate standardized provincial-level vaccine hesitancy rates, and multilevel logistic models were used to examine influencing factors, including sociodemographic characteristics and construct

SUBMITTER: Xie T 

PROVIDER: S-EPMC12931913 | biostudies-literature | 2026 Dec

REPOSITORIES: biostudies-literature