Higher serum uric acid levels are associated with an increased risk of carotid atherosclerosis in 67,256 adults.

ABSTRACT:

Background

The association between serum uric acid (SUA) and carotid atherosclerosis (CAS) remains controversial, particularly regarding its independence from traditional risk factors. This cross-sectional study aimed to investigate this relationship and its dose-response pattern in 67,256 adults.

Methods

We conducted a cross-sectional analysis of 67,256 participants who underwent health check-up at Beijing MJ Healthcare Center between 2012 and 2022. Data collected included demographics, physical exams, laboratory tests, and carotid ultrasound. Participants were divided into quartiles based on baseline SUA levels. Multivariate logistic regression analysis was performed with four models to assess the association between SUA and CAS, as well as its subtypes, including increase

SUBMITTER: Chen R 

PROVIDER: S-EPMC12932208 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature