Diagnostic accuracy of AMH for primary ovarian insufficiency/premature ovarian failure: a real-world cohort study.

ABSTRACT:

Background/objectives

The global incidence of Premature Ovarian Insufficiency (POI)/Primary Ovarian Failure (POF) is rising annually, emerging as a critical health threat affecting women of reproductive age. This condition not only induces menopausal-like symptoms but also leads to severe consequences such as infertility, imposing significant physical, familial, and socioeconomic burdens. Given its detrimental impacts, enhancing preventive strategies is imperative. Anti-Müllerian Hormone (AMH), closely associated with ovarian reserve, has gained increasing application in gynecological diagnostics, particularly exhibiting considerable potential in POI/POF evaluation. However, the diagnostic reliability of AMH remains to be fully elucidated. This study aims to rigorously evaluate the

SUBMITTER: Mao S 

PROVIDER: S-EPMC12932242 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature