A Single-Center, Open-Label Study to Evaluate the Efficacy and Tolerability of Retinal Encapsulated in a Novel Biomimetic Exosome in the Treatment of Mild-To-Moderate Facial Photodamage.

ABSTRACT:

Background

Numerous retinoid-based skincare products are available over-the-counter for photodamaged and photoaged skin, but are associated with objective (e.g., erythema, dryness, flaking, edema) and subjective (e.g., itching, tingling, stinging, burning) tolerability issues. A novel retinal formulation was developed using an engineered biomimetic vegan exosome as a delivery system. The formulation also contains proprietary and potent hyaluronic acid, as well as plant-based actives commonly used in traditional herbal medicines for their anti-inflammatory and antioxidant properties.

Aims

Evaluate the efficacy and tolerability of this biomimetic exosome-encapsulated retinal product for treatment of mild-to-moderate facial photodamage.

Patients/methods

Twenty females ag

SUBMITTER: Gold MH 

PROVIDER: S-EPMC12932260 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature