Surgical Antibiotic Prophylaxis Utilization and Predictors of Surgical Site Infections at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia: Prospective Cohort Study.

ABSTRACT:

Background

Surgical site infections (SSIs) are a major postoperative complication, particularly in resource-limited settings such as Ethiopia. Despite evidence-based guidelines, inappropriate surgical antibiotic prophylaxis (SAP) remains common. This study is aimed at assessing SAP utilization patterns, SSI prevalence, and associated factors at Debre Tabor Comprehensive Specialized Hospital.

Methods

A prospective cohort study was conducted among 342 surgical patients from February 1 to May 30, 2025. Adherence of SAP was assessed based on standard national and international guidelines. Descriptive, bivariate, and multivariable analyses were conducted using IBM SPSS software Version 27. Statistical significance was set at p < 0.05.

Results

Preoperative prophylaxi

SUBMITTER: Ferede YA 

PROVIDER: S-EPMC12932327 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature