Does time spent upright moderate the influence of a weighted vest on change in bone mineral density during weight loss among older adults? A secondary analysis of the INVEST in bone health randomized controlled trial.

ABSTRACT:

Introduction

The INVEST in Bone Health randomized controlled trial examined whether 1 year of weight loss paired with resistance training (WL+RT) or weighted vest use (WL+VEST) sustained bone mineral density (BMD) at the hip better than weight loss alone (WL). All groups lost similar amounts of body weight, but neither those wearing the vest nor those engaging in structured resistance training retained greater bone density relative to those in the weight loss-only condition. One possible reason for the absence of a group difference may be that the bone-sparing benefits of the weighted vest may relate to the amount of time one spends standing and therefore exposed to additional loading Purpose: The purpose of this secondary analysis was to determine whether the time an individual sp

SUBMITTER: Fanning J 

PROVIDER: S-EPMC12932580 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature