Hospital-onset methicillin-resistant <i>Staphylococcus aureus</i> bloodstream infections within tertiary and community hospitals and implications for prevention.

ABSTRACT:

Background

An improved understanding of the epidemiology of hospital-onset methicillin-resistant Staphylococcus aureus bloodstream infection (HO-MRSA BSI) could inform future prevention strategies for HO-MRSA BSI.

Methods

We performed a retrospective cohort study of HO-MRSA BSI reported to NHSN from 2020-2023 at a system of 9 acute care hospitals located in New York City. The primary outcome was to describe the demographic and clinical characteristics of patients with HO-MRSA BSI. Secondary outcomes included comparisons of tertiary (TH) and community (CH) hospitals, standardized infection ratio (SIR) and rates per 10,000 patient-discharges, presumptive potential infectious sources, and mortality.

Results

Between 2020 and 2023, 222 patients had HO-MRSA BSI. Thei

SUBMITTER: Singh HK 

PROVIDER: S-EPMC12932923 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature