<i>SiLNR1</i>-Mediated Nitrogen Regulatory Signaling Enhances Nitrogen Use Efficiency and Grain Yield in Foxtail Millet (<i>Setaria italica</i> L.) under Low-Nitrogen Stress.

ABSTRACT: Foxtail millet (Setaria italica L.), a C4 cereal crop domesticated in China, exhibits exceptional nitrogen use efficiency (NUtE) with marked genotypic variation; however, the molecular basis remains underexplored. Here, we identified candidate genes through a sequential filtering strategy from genetic linkage (bulked segregant analysis sequencing) to transcriptional response (RNA sequencing) within defined quantitative trait locus intervals to dissect NUtE mechanisms in contrasting genotypes: the low-nitrogen-tolerant variety Yugu28 and the low-nitrogen-sensitive variety Qiyehuang, to identify the genetic regulatory mechanisms. Several candidate genes were screened, such as glutamine synthetase (GS2, Seita.3G024100), glutathione S-transferase (GLUS, Seita.3G3860

SUBMITTER: Qin N 

PROVIDER: S-EPMC12932939 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature