Sleep Apnea-Specific Hypoxic Burden and Postoperative Outcomes of Major Noncardiothoracic Surgery.

ABSTRACT:

Importance

Obstructive sleep apnea (OSA) is a highly prevalent and heterogeneous condition that predisposes to postoperative complications. Adequate metrics of OSA severity to stratify postoperative risk in a clinical setting are needed.

Objective

To evaluate whether the sleep apnea-specific hypoxic burden (SASHB) is associated with postoperative cardiovascular (CV) complications and mortality among patients with OSA undergoing major noncardiothoracic surgery.

Design, setting, and participants

Multicenter clinic-based cohort linked with a health administrative database involving adult patients diagnosed with OSA between May 2007 and December 2018 who underwent major noncardiothoracic surgery between OSA diagnosis and December 2024. Data were analyzed from January to D

SUBMITTER: Bailly S 

PROVIDER: S-EPMC12933281 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature