Polybrominated Diphenyl Ethers, Occupational Exposures, and Thyroid Function Among US and Canadian Firefighters: A Cross-sectional Study.

ABSTRACT:

Objective

Evaluate the association between serum polybrominated diphenyl ether (PBDE) levels and thyroid anatomy and function in firefighters.

Methods

Two hundred fifty-nine firefighters provided a blood sample and underwent thyroid ultrasound. Blood serum levels were tested for thyroid function tests and PBDEs -47, -85, -99, -100, -153, and -154 (ng/g lipid weight). Ultrasonography documented structural characteristics. Bivariate associations between PBDE concentrations and demographic/occupational characteristics, thyroid function, and thyroid anatomic measures were determined using multivariable linear regression.

Results

A positive relationship between PBDE-47 and triiodothyronine ( P = 0.02) while an inverse relationship with free thyroxine ( P = 0.03) was observ

SUBMITTER: Gould Rothberg BE 

PROVIDER: S-EPMC12933983 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature