Antimicrobial metabolites of the intestinal fungus Trichoderma sp. QTYC44 from Pantala flavescens larvae.

ABSTRACT:

Background

Insect gut fungi are increasingly recognized as specialized microbial reservoirs of bioactive compounds, yet the insect-associated microbes of Pantala flavescens larvae remain understudied.

Results

In this study, the intestinal fungus Trichoderma sp. QTYC44, previously isolated from P. flavescens larvae, was further characterized and its antimicrobial metabolites were investigated. QTYC44 exhibited significant inhibitory effects on Fusarium oxysporum f. sp. cucumerinum with inhibition rates exceeding 80% and effectively suppressed cucumber wilt disease in a pot experiment, achieving 72.58% control efficacy. Chemical analysis of QTYC44 cultures led to the identification of 11 metabolites, including trichopyrone (1), bisvertinolone (2), vertinolide (3), (22E)-5a,8a-

SUBMITTER: Kong K 

PROVIDER: S-EPMC12934020 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature