Global threats in local wards: Dissemination of high-risk clones resistant to last-generation cephalosporins and carbapenems in Iraqi hospitals.

ABSTRACT:

Objectives

To conduct the first comprehensive molecular characterization of multidrug-resistant Gram-negative pathogens isolated from patients in six Iraqi hospitals.

Methods

Samples (n = 104) were collected from outpatients across six hospitals in Iraq between March and September 2022. Bacterial isolates were identified using standard microbiological techniques. Antimicrobial susceptibility testing was performed according to EUCAST guidelines. Genomic DNA was extracted and subjected to whole-genome sequencing (WGS).

Results

Over 104 samples, 42 resistant isolates were identified: Escherichia coli (n = 15), Klebsiella pneumoniae (n = 7), Pseudomonas aeruginosa (n = 15), and Acinetobacter baumannii (n = 5). WGS revealed genetic diversity, wi

SUBMITTER: Hashim EA 

PROVIDER: S-EPMC12934271 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature