Nematode-trapping devices of Arthrobotrys oligospora is an iron storage system mediated by elevated temperatures.

ABSTRACT: Under low-nutrient conditions, nematode-trapping fungi (NTFs) can differentiate their mycelia into specialized trapping devices for capturing prey. Using energy-dispersive X-ray spectroscopy in conjunction with transmission electron microscopy, together with a series of bioassay, we identified that the characteristic electron-dense bodies in trapping devices contained more iron than vacuoles and mitochondria, functioning as an unrecognized iron storage organelle. Genomic analysis revealed that all NTFs lack the Ccc1-mediated vacuolar iron detoxification mechanism conserved in most fungi. Heterogenous expression of yeast-derived Ccc1 gene in Arthrobotrys oligospora significantly reduced trapping device formation and nematicidal activity. Mapping key factor fluctuations onto Bayesian relaxed

SUBMITTER: Zhou J 

PROVIDER: S-EPMC12934349 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature