What are the symptoms and concerns of young adults living with life-limiting conditions and how well are they captured by patient reported outcome measures? A mixed-methods systematic review and framework synthesis.

ABSTRACT:

Background

Internationally the number of young adults living with life-limiting conditions is increasing. Holistic concerns of this population have not been reviewed. It is unclear whether patient reported outcome measures used in this population capture their symptoms and concerns.

Aims

To: (1) identify and synthesise the symptoms and concerns of young adults (aged 18-39) living with life-limiting conditions; (2) evaluate the content validity of patient reported outcome measures used in this population.

Design

A mixed-methods systematic review and framework synthesis. PROSPERO ID CRD42024565986.

Data sources

MEDLINE, EMBASE, Cochrane, CINAHL, PsycINFO, AMED from inception to 04/07/24.

Results

A total of 16552 articles identified, 100 included. Among the

SUBMITTER: Chambers RL 

PROVIDER: S-EPMC12936152 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature