Electrochemical/Colorimetric Dual-Mode Aptasensor Based on CuZr-MOF and Fe₃O₄@ZIF-8 for Detection of Malathion in Vegetables.

ABSTRACT: In on-site rapid detection, the electrochemical method boasts high sensitivity and rapid response capabilities, while the colorimetric method can provide intuitive visual readings suitable for on-site screening. Therefore, this study developed an innovative dual-mode electrochemical/colorimetric aptasensor for the accurate detection of malathion (MAL) in vegetables. The sensor combines magnetic Fe₃O₄@ZIF-8-DNA composites and CuZr-MOF-cDNA probes, enabling simultaneous detection of the target through electrochemical reactions and colorimetric changes. The introduction of CuZr-MOF not only enhances the sensor's conductivity but also significantly amplifies the electrochemical signal through its catalytic properties. The magnetic Fe₃O₄@ZIF-8-DNA com

SUBMITTER: Liu K 

PROVIDER: S-EPMC12937831 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature