MicroRNA Expression Profile in Endometriosis and Endometriosis-Associated Ovarian Cancer-Systematic Review.

ABSTRACT: Endometriosis-associated ovarian cancer comprises a special group of ovarian cancers that most probably originate from endometriosis foci. Several in vitro studies have shown that microRNA (miRNA) plays an important role in this carcinogenesis. Our goal was to establish if a distinct miRNA profile can be associated with endometriosis and endometriosis-associated ovarian cancer with their potential causal relationship, and whether such a profile could be used clinically to prognose carcinogenesis in endometriosis foci. We conducted a systematic search according to PRISMA guidelines, registered at PROSPERO (number CRD42021245606). The search encompassed whole Pubmed, Cochrane and Medline databases to 1 May 2025 and the search strategy included the following [MeSH] terms: 'miRNAs' or 'microRN

SUBMITTER: Szubert M 

PROVIDER: S-EPMC12939174 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature