Integrated Transcriptomic and Metabolomic Analysis Reveals Molecular Signatures Associated with Natural Degeneration of <i>Puccinia striiformis</i> f. sp. <i>tritici</i>.

ABSTRACT: Stripe rust of wheat, caused by the obligate biotrophic fungus Puccinia striiformis f. sp. tritici (Pst), is a devastating disease. The natural degeneration and viability loss of Pst urediniospores directly impact its dispersal and epidemic potential, yet the underlying molecular mechanisms remain unclear. This study aimed to systematically decipher the key molecular changes during the natural degeneration of Pst urediniospores using a multi-omics approach. We performed integrated transcriptomic (RNA-seq) and metabolomic (LC-MS) analyses on relatively purified fresh urediniospores (CC group) and those undergoing room-temperature-induced degeneration (CM group) of the prevalent Pst race CYR34. A total of 1622 differentially expressed genes (DEGs) and 382 differentially accumul

SUBMITTER: Yuan C 

PROVIDER: S-EPMC12939390 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature