Prospective evaluation of clinical prediction rules for brief resolved unexplained event.

ABSTRACT:

Objectives

Published clinical prediction rules propose to determine risks of event recurrence and serious underlying condition in infants with brief resolved unexplained event (BRUE). The objective of this study was to evaluate these rules in a prospectively recruited cohort of infants with BRUE to test the hypothesis that the rules may be helpful in predicting risk but their test characteristics may differ from those previously reported.

Methods

To determine the validity of prediction rules for risk of recurrent events and serious diagnoses, we applied the calculators to patients with BRUE who were prospectively recruited at our institution. Infants were recruited during their index hospitalization, caregiver-reported symptoms were obtained by questionnaires during the 6-mo

SUBMITTER: Duncan DR 

PROVIDER: S-EPMC12940885 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature