An Ammonium Transporter Gene Contributes to the Aggressiveness of the Dutch Elm Disease Pathogen <i>Ophiostoma novo-ulmi</i>.

ABSTRACT: Molecular mechanisms determining pathogenicity of the Dutch elm disease fungus Ophiostoma novo-ulmi are poorly understood. Prior identification of the pathogenicity locus pat1 prompted a chromosome walking approach to elucidate gene function in this region. Among 17 identified genes, ONUg0282 (amtA) was predicted to encode a high-affinity ammonium transporter. In silico analyses confirmed the presence of four additional amt genes (amtB, amtC, amtD, and amtE) in both O. novo-ulmi and the less aggressive O. ulmi and that amtA and amtB belong to the Saccharomyces cerevisiae mep2 clade. The predicted amtA gene product showed features of Mep2-type transceptors, including amino acid residues

SUBMITTER: Bernier L 

PROVIDER: S-EPMC12941551 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature