Development and Validation of Cardiorespiratory Fitness Prediction Equations from 6-Minute Walk Test in the CARDIA Study.

ABSTRACT:

Background

Assessing maximal oxygen consumption (VO2max), the gold standard for assessing cardiorespiratory fitness (CRF), is often impractical in large-scale studies. We derived sex-specific VO2max and graded exercise test duration (GXTd) prediction equations from 6-minute walk test (6MWT) performance.

Methods

Data were from 564 Coronary Artery Risk Development in Young Adults (CARDIA) participants (mean age: 61.5 years; 58% women; 40% Black) who completed the 6MWT and symptom-limited modified Balke treadmill GXT at the Year 35 (2021-22) follow-up exam. Sex-stratified samples were randomly split (2/3 for training, 1/3 for testing) to derive and evaluate prediction equations. Stepwise linear regression identified predictors of VO2max and GXTd from 6MWT distance. Sex-specific

SUBMITTER: Hornikel B 

PROVIDER: S-EPMC12944221 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature