Investigating the optimum timeline for final cure assessment of treated Visceral Leishmaniasis patients in Bangladesh.

ABSTRACT: Bangladesh became the first country globally to receive validation for the public health elimination of Visceral Leishmaniasis (VL). However, while VL cases have declined, sequels such as treatment failure and relapse are increasing. The current practice of assessing VL cure at six months post-treatment may delay the identification of sequelae. This study aims to determine the time required for VL patients to achieve complete clinical recovery and parasitological clearance, contributing to sustainable elimination efforts. We enrolled 50 confirmed VL patients from VL-endemic subdistricts of Mymensingh between June 2016 and March 2018. All the enrolled patients were treated with a single dose of Liposomal Amphotericin B (LAmB) (10 mg/kg intravenous infusion). Blood samples were collected upo

SUBMITTER: Sagar SK 

PROVIDER: S-EPMC12944797 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature