Immunoendocrine Profiles in Neurocysticercosis Patients: A Case-Control Study in Honduras.

ABSTRACT: Emerging evidence suggests that certain cestodes, including Taenia solium, may actively modulate the host's hormonal and immune environment to facilitate their survival. This study aimed to determine whether patients diagnosed with neurocysticercosis (NCC) exhibit immunoendocrine alterations associated with infection. A clinical study was conducted in Honduras, enrolling 11 adult NCC patients (9 female, 2 male) and 11 age- and sex-matched healthy controls. Serum concentrations of seven hormones and two cytokines were evaluated. Compared to controls, NCC patients showed significantly elevated levels of 17β-Estradiol (E2), Progesterone (P4), Androstenedione (A4), Luteinizing Hormone (LH), Follicle-Stimulating Hormone (FSH), Interleukin-6 (IL-6), and Interleukin-10 (IL-10). Conversely,

SUBMITTER: Zugno-Gadea N 

PROVIDER: S-EPMC12944953 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature