Robust Goat-Derived <i>Enterococcus</i> Isolates with Broad-Spectrum Antipathogenic Activity as Next-Generation Probiotic Candidates.

ABSTRACT: The rise of multidrug-resistant enteric pathogens and increased demand for antibiotic alternatives have intensified efforts to find reliable, safe, and effective probiotics. This study reports the isolation, characterization, and assessment of the probiotic potential of five Enterococcus strains isolated from the feces of healthy goats aged 7-9 months raised under conventional management. Following an initial screening of 57 lactic acid bacteria, 5 isolates (Enterococcus faecium, E. hirae, E. faecalis, Enterococcus sp., and Streptococcus lutetiensis) were chosen based on their catalase-negative, non-motile, and non-hemolytic characteristics, in addition to their high tolerance to gastric (pH 2.0) and intestinal (pH 8.0, 0.3-1.5% bile salt) stress.

SUBMITTER: Essa MOA 

PROVIDER: S-EPMC12945012 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature