Acoustic Emission Biomarkers for the Detection and Monitoring of Early Knee Osteoarthritis: Protocol for a Prospective, Single-Center, Exploratory Study.

ABSTRACT:

Background

Osteoarthritis is a highly prevalent and disabling condition. In early stages, patients are asymptomatic or only experience activity-related pain. When pain intensifies, the disease has often progressed, with few treatment options besides knee arthroplasty. Recently, there has been a growing interest in acoustic emissions generated by poorly lubricated and/or damaged moving joint surfaces, as seen in osteoarthritis. Noninvasive analysis of knee sound could help identify patients with early-stage osteoarthritis at a low cost, without radiation exposure. Thus, preventive measures could be implemented earlier and delay the progression of osteoarthritis.

Objective

This study aims to identify acoustic biomarkers with prognostic value for the early detection of osteoart

SUBMITTER: Leuthard L 

PROVIDER: S-EPMC12945087 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature