ABSTRACT: In this study, we investigated the bioaccumulation of 17 heavy metals-titanium, vanadium, chromium, manganese, iron, cobalt, nickel, copper, zinc, arsenic, selenium, molybdenum, antimony, cadmium, tin, mercury, and lead-in the liver and kidney tissues of the least weasel, based on samples (n = 129) collected from adjacent intensive agricultural environments in Hungary and Austria. To explore the structure of the bioaccumulation data, principal component analysis (PCA) was performed. The PCA score plot based on national-level elemental profiles revealed no differentiation between Austria and Hungary. In contrast, a clear and unambiguous distinction was observed between the two examined tissues within individuals for Ti, Mn, Fe, Co, Zn, Se, Mo, Cd, and Hg (p < 0.001), as well as for P