Integrated Molecular and Hematobiochemical Biomarkers for the Detection of Bovine Babesiosis in Holstein Calves.

ABSTRACT: Bovine babesiosis is a widespread tick-borne parasitic disease that compromises calf health and productivity, causing substantial economic losses. This study evaluated the potential of molecular and hematobiochemical biomarkers for the detection of babesiosis in Holstein calves by analyzing the expression dynamics of selected immune and antioxidant genes and their association with blood-based indicators. Blood samples were collected from 243 fattening calves, classified as healthy (n = 180) or naturally infected (n = 63). Transcriptional levels of immune-related genes (IL-2, IL-6, TNF-α, and MCP-1) and antioxidant genes (SOD3, CAT, GPX, and GST) were measured alongside hematological, biochemical, immunological, and oxida

SUBMITTER: Alqhtani HA 

PROVIDER: S-EPMC12945156 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature