Fast multi-resolution 3D printing of microfluidics: enabling 2 μm channels and ultra-compact mixers.

ABSTRACT: Microfluidic devices with ultra-fine features are critical for applications in biomedical diagnostics, chemical analysis, and lab-on-chip systems, but achieving high-resolution negative features with fast print times remains a significant challenge due to limitations in conventional 3D printing techniques. Motivated by the need for rapid fabrication of precise, compact microfluidic structures to enhance performance and miniaturization, we present an efficient multi-resolution 3D printing technique designed to fabricate microfluidic devices with exceptionally high-resolution negative features. For instance, we achieve fully enclosed channels with cross sections as small as 1.9 µm × 2.0 µm, a two-order-of-magnitude reduction in cross-sectional area compared to the 18 µm × 20 µm channels repo

SUBMITTER: Miner DS 

PROVIDER: S-EPMC12946173 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature