The effect of OsteoStrong compared to dynamic multicomponent exercise on bone strength in older women: the BONEMORE non-inferiority randomized controlled trial.

ABSTRACT: The efficacy of OsteoStrong® (OS) on bone strength is limited, and how it compares to dynamic multicomponent exercise (DME) is unknown. In this randomized controlled trial, the effect of OS on bone material strength index (BMSi) in older women was non-inferior to that of DME. No significant interaction between treatment and time was observed in any measured outcomes, indicating no meaningful difference between the intervention groups. Although the OsteoStrong® intervention met the pre-specified non-inferiority margin compared to the DME group, the lack of efficacy of the DME intervention on BMSi limits the interpretation of this finding.

Purpose

The aim of this study was to investigate whether the effect of using OS was non-inferior to DME for the primary outcome of BMSi in older wo

SUBMITTER: Lindberg PWS 

PROVIDER: S-EPMC12946272 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature