Cross-Sectional and Longitudinal Analyses of the Association Between Statin Use and Age-Related Hearing Loss.

ABSTRACT:

Background

Emerging evidence in animal models and humans suggests that statins may provide partial protection against noise-induced and drug-induced hearing loss. However, evidence for protection against age-related hearing loss (ARHL) is mixed, and longitudinal studies in large adult cohorts from the general population are limited. This study examined the association between statin use and ARHL in a diverse, community-based longitudinal cohort of adults across the lifespan.

Methods

The 1239 participants, aged ≥ 55 years, are from the MUSC Longitudinal Cohort Study of Age-Related Hearing Loss (1988-present). Following a comprehensive baseline examination, participants attended annual examinations during which audiometric and statin use data were collected. Multivariable line

SUBMITTER: Maldonado LG 

PROVIDER: S-EPMC12946368 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature