Association of sleep disorder with increased risk of gallstone disease in adults in the United States: A cross-sectional study of the National Health and Nutrition Examination Survey (2017-2020).

ABSTRACT: ObjectiveSleep disorder is prevalent in modern society and has been linked to multiple adverse health outcomes; however, evidence regarding its association with gallstone disease remains limited. This study aimed to investigate the association between sleep disorder and gallstones among adults in the United States.MethodsWe conducted a cross-sectional analysis of data from 7438 adults in the United States aged ≥20 years who participated in the National Health and Nutrition Examination Survey (2017-2020). The relationship between sleep disorder and gallstones was assessed using multivariable logistic regression models, with sensitivity analyses performed using multiple imputation, weighted analysis, and propensity score matching.ResultsAmong all participants, 780 (10.5%) reported gallstones

SUBMITTER: Zhuang Y 

PROVIDER: S-EPMC12946423 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature