An Ustilaginoidea virens Nuclear Effector SCRE7 Inhibits Rice Immunity via Suppressing OsLBD11/12-Promoted Transcription of OsCPS2.

ABSTRACT: Phytopathogenic fungi secrete a great number of effector proteins into various organelles of host plants and suppress plant immunity through different mechanisms. In this study, we identify SCRE7 as a unique nuclear effector that is essential for U. virens infection. SCRE7 interacts with a transcription factor OsLBD11/12 in rice nuclei. Interestingly, defence responses and rice resistance against bacterial and fungal diseases are negatively modulated by SCRE7, but positively regulated by OsLBD11/12. Consistently, transcriptome analyses revealed that SCRE7 and OsLBD11/12 oppositely regulate multiple immune-related pathways in rice. Furthermore, we demonstrated that OsLBD11/12 activates the transcription of OsCPS2 encoding a positive immune regulator through specifically binding to the cis-e

SUBMITTER: Jiang C 

PROVIDER: S-EPMC12946497 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature