TaSPX3 Enhances Wheat Resistance to Leaf Rust by Antagonising TaDi19-Mediated Repression of Pathogenesis-Related Genes.

ABSTRACT: Wheat leaf rust, caused by Puccinia triticina (Pt), threatens global wheat production, with yield losses further exacerbated by the pathogen's evolving virulence. Although Syg1/Pho81/Xpr1 (SPX) domain-containing proteins are known regulators of phosphate homeostasis, their involvement in plant-pathogen interactions remains largely unexplored. We demonstrated that TaSPX3, a wheat SPX family gene, is rapidly induced during early Pt infection and flg22 treatment. Genetic evidence indicates that TaSPX3 is a positive regulator of rust resistance, with knockdown lines showing increased susceptibility and overexpression lines exhibiting enhanced resistance. Using yeast two-hybrid screening, we identified TaDi19-1D, a zinc finger transcription factor, as a direct TaSPX3 interactor. TaDi19-1D funct

SUBMITTER: Qian H 

PROVIDER: S-EPMC12946499 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature