Associations Between Depression Severity, Antidepressant Use, and Metabolic Syndrome Components Among Chinese Adults: A Cross-Sectional Study Based on Historical Medical Records.

ABSTRACT:

Background

Depression affects approximately 280 million people globally and often co-occurs with metabolic syndrome (MetS), a cluster of cardiometabolic risks that increase cardiovascular and diabetes events. This study investigates the associations among depression severity, antidepressant use and MetS components in Chinese adults.

Methods

In this cross-sectional study from a Chinese hospital (2018-2025), electronic medical records of 585 adults (aged ≥18 years, 61.54% female) were analysed using convenience sampling. Depression severity was assessed via Patient Health Questionnaire-9 (PHQ-9) scores (normal: 0-4; mild: 5-9; moderate: 10-14; severe: 15-27). MetS was defined in accordance with the National Cholesterol Education Program Adult Treatment Panel III criteria (≥thr

SUBMITTER: Hu Y 

PROVIDER: S-EPMC12946717 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature