Transient Global Amnesia and High-Grade Styloidogenic Jugular Vein Stenosis.

ABSTRACT:

Importance

Pathogenesis of focal hippocampal ischemia in transient global amnesia (TGA) remains unclear but may be of venous origin. Brain magnetic resonance imaging (MRI)-restricted diffusion has considerable limitations as the only current TGA imaging marker, highlighting a critical need for more reliable disease determinants.

Objective

To assess whether the severity of unilateral or bilateral styloidogenic jugular vein compression (SJVC), which can impair intracranial venous drainage, could serve as a novel adjunctive imaging risk factor associated with TGA diagnosis.

Design, setting, and participants

This retrospective case-control study of patients with TGA and hippocampal-restricted diffusion and without TGA but with hippocampal-restricted diffusion and healthy

SUBMITTER: Muneer MS 

PROVIDER: S-EPMC12947034 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature