Diphtheria seroprotection among Indonesian children: Community Health Surveys Riskesdas 2007, 2013 and 2018.

ABSTRACT: Diphtheria remains a public health concern in Indonesia despite long-standing inclusion of diphtheria-containing vaccines in the national immunization program. This study assessed temporal trends in diphtheria immunity among Indonesian children aged 1-14 years, identified vulnerable age groups, and examined factors associated with seroprotection. We analyzed diphtheria IgG antibody data measured by ELISA from the Indonesian Community Health Surveys (Riskesdas) conducted in 2007, 2013, and 2018. The analysis included 6,622 children (2007), 7,110 (2013), and 7,203 (2018). Bivariate and multivariate logistic regression analyses were performed to identify determinants of seroprotection. Across all surveys, diphtheria IgG levels were lowest at ages 1-6 years, increased at ages 7-10 years, and d

SUBMITTER: Hartanti MD 

PROVIDER: S-EPMC12948082 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature