Association between hemoglobin/red blood cell distribution width ratio and acute kidney injury in sepsis and heart failure patients.

ABSTRACT:

Introduction

The hemoglobin/red blood cell distribution width (Hb/RDW) ratio has emerged as a potential biomarker for acute kidney injury (AKI), particularly in patients with cardiovascular conditions. This study investigated the relationship between Hb/RDW ratio and AKI incidence in critically ill patients diagnosed with sepsis and heart failure (HF).

Methods

A retrospective study was conducted with 119 critically ill patients with sepsis and 83 patients with HF, analyzed according to the presence or absence of kidney injury. Multivariable logistic regression identified independent predictors of AKI. Outcomes between higher and lower Hb/RDW groups were compared.

Results

Patients who developed AKI showed higher C-reactive protein levels, elevated RDW (15.7 ± 2.2 vs. 1

SUBMITTER: Mendonca Dos Santos P 

PROVIDER: S-EPMC12948117 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature