Health care utilization and costs associated with acute exacerbation of fibrosing interstitial lung disease in the United States: A retrospective administrative claims database analysis.

ABSTRACT:

Background

Interstitial lung disease (ILD) is a diverse group of pulmonary disorders characterized by inflammation and fibrosis of the lung parenchyma. Previous studies have linked acute exacerbation (AEx) events in patients with idiopathic pulmonary fibrosis to frequent hospitalizations, increased health care resource utilization (HCRU), and high mortality. However, limited information exists regarding the impact of AEx in other forms of fibrosing ILD.

Objective

To assess HCRU and the associated costs of managing AEx in patients within a large population of patients with fibrosing ILD.

Methods

This retrospective cohort study used a large US claims database to identify adults (aged ≥18 years) with fibrosing ILD who experienced at least 1 AEx event between January 2017

SUBMITTER: Yang J 

PROVIDER: S-EPMC12948750 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature