Systematic Review: Antipsychotic Medication in Pregnancy and Neurodevelopmental Outcomes in Children.

ABSTRACT:

Objective

Antipsychotic medications are widely prescribed, including during pregnancy, and pregnant individuals worry about the potential sequelae for the child. Although antipsychotics do not seem to be teratogenic, the long-term neurodevelopmental impact of prenatal exposure remains unclear. A systematic review was conducted to determine if intrauterine antipsychotic exposure increases the risk of adverse neurodevelopmental outcomes.

Method

A systematic search was performed in MEDLINE, Cochrane, Embase, and PsycINFO for studies published before September 7, 2024. We included original studies assessing cognitive, motor, behavioral, social, and psychiatric outcomes in children prenatally exposed to antipsychotics, excluding case reports, reviews, preclinical studies, and stu

SUBMITTER: Kaplan CA 

PROVIDER: S-EPMC12949658 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature