National Trends in Cerebrovascular Disease-Related Mortality among Adults With Obesity in the United States, 1999-2020.

ABSTRACT:

Background

Cerebrovascular disease (CVD) remains a leading cause of death, with obesity exacerbating stroke risk through multiple metabolic pathways. However, long-term trends in CVD-related mortality among obese adults in the United States remain inadequately defined.

Methods

We analyzed national mortality data from 1999 to 2020 using the CDC WONDER database. Deaths were included if CVD (ICD-10 I60-I69) was the underlying cause and obesity (E66) a contributing cause. Age-adjusted mortality rates (AAMRs) were calculated, and temporal trends were evaluated using Joinpoint regression to estimate annual percent change (APC) and average annual percent change (AAPC).

Results

From 1999 to 2020, 26,410 CVD-related deaths occurred among obese adults. The overall AAMR was 0.53

SUBMITTER: Hassan IN 

PROVIDER: S-EPMC12949721 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature