Quantification of the effect of vaccination on transmission of avian influenza (H7N7) in chickens.

ABSTRACT: Recent outbreaks of highly pathogenic avian influenza (HPAI) viruses in poultry and their threatening zoonotic consequences emphasize the need for effective control measures. Although vaccination of poultry against avian influenza provides a potentially attractive control measure, little is known about the effect of vaccination on epidemiologically relevant parameters, such as transmissibility and the infectious period. We used transmission experiments to study the effect of vaccination on the transmission characteristics of HPAI A/Chicken/Netherlands/03 H7N7 in chickens. In the experiments, a number of infected and uninfected chickens is housed together and the infection chain is monitored by virus isolation and serology. Analysis is based on a stochastic susceptible, latently infected, i

SUBMITTER: van der Goot JA 

PROVIDER: S-EPMC1312373 | biostudies-literature | 2005 Dec

REPOSITORIES: biostudies-literature