An aflatoxin biosynthesis cluster gene encodes a novel oxidase required for conversion of versicolorin a to sterigmatocystin.

ABSTRACT: Disruption of the aflatoxin biosynthesis cluster gene aflY (hypA) gave Aspergillus parasiticus transformants that accumulated versicolorin A. This gene is predicted to encode the Baeyer-Villiger oxidase necessary for formation of the xanthone ring of the aflatoxin precursor demethylsterigmatocystin.

SUBMITTER: Ehrlich KC 

PROVIDER: S-EPMC1317430 | biostudies-literature | 2005 Dec

REPOSITORIES: biostudies-literature