Ontology highlight
ABSTRACT:
SUBMITTER: Kraft C
PROVIDER: S-EPMC1317581 | biostudies-literature | 2006 Jan
REPOSITORIES: biostudies-literature
Journal of bacteriology 20060101 1
The gastric pathogen Helicobacter pylori shows tremendous genetic variability within human populations, both in gene content and at the sequence level. We investigated how this variability arises by comparing the genome content of 21 closely related pairs of isolates taken from the same patient at different time points. The comparisons were performed by hybridization with whole-genome DNA microarrays. All loci where microarrays indicated a genomic change were sequenced to confirm the events. The ...[more]