DNA replication: a complex matter.
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ABSTRACT:
SUBMITTER: Frouin I
PROVIDER: S-EPMC1326325 | biostudies-literature | 2003 Jul
REPOSITORIES: biostudies-literature
Publications
DNA replication: a complex matter.
Frouin Isabelle I Montecucco Alessandra A Spadari Silvio S Maga Giovanni G
EMBO reports 20030701 7
In eukaryotic cells, the essential function of DNA replication is carried out by a network of enzymes and proteins, which work together to rapidly and accurately duplicate the genetic information of the cell. Many of the components of this DNA replication apparatus associate with other cellular factors as components of multiprotein complexes, which act cooperatively in networks to regulate cell cycle progression and checkpoint control, but are distinct from the pre-replication complexes that ass ...[more]
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