FLIGHT: database and tools for the integration and cross-correlation of large-scale RNAi phenotypic datasets.

ABSTRACT: FLIGHT (www.flight.licr.org) is a new database designed to help researchers browse and cross-correlate data from large-scale RNAi studies. To date, the majority of these functional genomic screens have been carried out using Drosophila cell lines. These RNAi screens follow 100 years of classical Drosophila genetics, but have already revealed their potential by ascribing an impressive number of functions to known and novel genes. This has in turn given rise to a pressing need for tools to simplify the analysis of the large amount of phenotypic information generated. FLIGHT aims to do this by providing users with a gene-centric view of screen results and by making it possible to cluster phenotypic data to identify genes with related functions. Additionally, FLIGHT provides microarray express

SUBMITTER: Sims D 

PROVIDER: S-EPMC1347401 | biostudies-literature | 2006 Jan

REPOSITORIES: biostudies-literature