DBD: a transcription factor prediction database.

ABSTRACT: Regulation of gene expression influences almost all biological processes in an organism; sequence-specific DNA-binding transcription factors are critical to this control. For most genomes, the repertoire of transcription factors is only partially known. Hitherto transcription factor identification has been largely based on genome annotation pipelines that use pairwise sequence comparisons, which detect only those factors similar to known genes, or on functional classification schemes that amalgamate many types of proteins into the category of 'transcription factor'. Using a novel transcription factor identification method, the DBD transcription factor database fills this void, providing genome-wide transcription factor predictions for organisms from across the tree of life. The prediction

SUBMITTER: Kummerfeld SK 

PROVIDER: S-EPMC1347493 | biostudies-literature | 2006 Jan

REPOSITORIES: biostudies-literature