Characterization of a strain of community-associated methicillin-resistant Staphylococcus aureus widely disseminated in the United States.

ABSTRACT: A highly stable strain of Staphylococcus aureus with a pulsed-field gel electrophoresis type of USA300 and multilocus sequence type 8 has been isolated from patients residing in diverse geographic regions of the United States. This strain, designated USA300-0114, is a major cause of skin and soft tissue infections among persons in community settings, including day care centers and correctional facilities, and among sports teams, Native Americans, men who have sex with men, and military recruits. The organism is typically resistant to penicillin, oxacillin, and erythromycin (the latter mediated by msrA) and carries SCCmec type IVa. This strain is variably resistant to tetracycline [mediated by tet(K)]; several recent isolates have decreased susceptibility to fluoroquinolones. S. aureus USA3

SUBMITTER: Tenover FC 

PROVIDER: S-EPMC1351972 | biostudies-literature | 2006 Jan

REPOSITORIES: biostudies-literature